Can you bill multiple initial IV infusions codes in the same encounter? Generally, coding guidelines allow for only one "initial" infusion code per encounter. However, reporting two initial codes (e.g., CPT 96365 and 96365-59) is permitted when it is medical necessary for separate IV access and it is clearly documented. This usually occurs due to medication incompatibility, high-volume resuscitation, or specific drug protocols. In this guide, we will break down how to use Epi